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    Last years of nuclear medicine related articles



    Please, see plubications on staff site



    Please, see plubications on staff site



    Trägårdh E, Ljungberg M, Edenbrandt L, Örndahl E, Johansson L, Gustafsson A, Jonsson C, Hagerman J, Riklund K, Minarik D. Evaluation of inter-departmental variability of ejection fraction and cardiac volumes in myocardial perfusion scintigraphy using simulated data. EJNMMI Phys. 2015 Dec;2(1):2. doi: 10.1186/s40658-014-0105-9. Epub 2015 Jan 23. PubMed PMID: 26501804; PubMed Central PMCID: PMC4545220

    Anand A, Morris MJ, Kaboteh R, Båth L, Sadik M, Gjertsson P, Lomsky M, Edenbrandt L, Minarik D, Bjartell A. Analytical Validation of the Automated Bone Scan Index as an Imaging Biomarker to Standardize the Quantitative Changes in Bone Scans of Patients with Metastatic Prostate Cancer. J Nucl Med. 2015 Aug 27. pii: jnumed.115.160085. [Epub ahead of print] PubMed PMID: 26315832.

    Minarik D, Senneby M, Wollmer P, Mansten A, Sjöstrand K, Edenbrandt L, Trägårdh E. Perfusion vector-a new method to quantify myocardial perfusion scintigraphy images: a simulation study with validation in patients. EJNMMI Res. 2015 Dec;5(1):121. doi: 10.1186/s13550-015-0121-3. Epub 2015 Aug 14. PubMed PMID: 26268545; PubMed Central PMCID: PMC4534480.

    Poulsen MH, Rasmussen J, Edenbrandt L, Høilund-Carlsen PF, Gerke O, Johansen A, Lund L. Bone Scan Index predicts outcome in patients with metastatic hormone sensitive prostate cancer. BJU Int. 2015 Apr 24. doi: 10.1111/bju.13160. [Epub ahead of print] PubMed PMID: 25906907.

    Nakajima K, Matsuo S, Wakabayashi H, Yokoyama K, Bunko H, Okuda K, Kinuya S, Nyström K, Edenbrandt L. Diagnostic Performance of Artificial Neural Network for Detecting Ischemia in Myocardial Perfusion Imaging. Circ J. 2015 Apr 3. [Epub ahead of print] PubMed PMID: 25843558.

    Trägårdh E, Hesse B, Knuuti J, Flotats A, Kaufmann PA, Kitsiou A, Hacker M, Verberne HJ, Edenbrandt L, Delgado V, Donal E, Edvardsen T, Galderisi M, Habib G, Lancellotti P, Nieman K, Rosenhek R; EACVI, Agostini D, Gimelli A, Lindner O, Slart R, Ubleis C; EANM. Reporting nuclear cardiology: a joint position paper by the European Association of Nuclear Medicine (EANM) and the European Association of Cardiovascular Imaging (EACVI). Eur Heart J Cardiovasc Imaging. 2015
    Mar;16(3):272-9. doi: 10.1093/ehjci/jeu304. Epub 2015 Jan 23. PubMed PMID: 25618478.

    Trägårdh E, Carlsson M, Edenbrandt L. Computerized decision making in myocardial perfusion SPECT: The new era in nuclear cardiology? J Nucl Cardiol. 2015 Oct; 22(5):885-7. Epub 2014 PubMed PMID: 25500801.


    Reza M, Bjartell A, Ohlsson M, Kaboteh R, Wollmer P, Edenbrandt L, Trägårdh E. Bone Scan Index as a prognostic imaging biomarker during androgen deprivation therapy. EJNMMI Res. 2014 Oct 17;4:58. doi: 10.1186/s13550-014-0058-y. eCollection 2014. PubMed PMID: 25386390; PubMed Central PMCID: PMC4205473.

    Brolin G, Edenbrandt L, Granerus G, Olsson A, Afzelius D, Gustafsson A, Jonsson C, Hagerman J, Johansson L, Riklund K, Ljungberg M. The accuracy of quantitative parameters in (99m) Tc-MAG3 dynamic renography: a national audit based on virtual image data. Clin Physiol Funct Imaging. 2014 Oct 28. doi: 10.1111/cpf.12208. [Epub ahead of print] PubMed PMID: 25348641.

    Armstrong AJ, Kaboteh R, Carducci MA, Damber JE, Stadler WM, Hansen M, Edenbrandt L, Forsberg G, Nordle Ö, Pili R, Morris MJ. Assessment of the bone scan index in a randomized placebo-controlled trial of tasquinimod in men with metastatic castration-resistant prostate cancer (mCRPC). Urol Oncol. 2014 Nov;32(8):1308-16. doi: 10.1016/j.urolonc.2014.08.006. Epub 2014 Sep 16. PubMed PMID: 25240761

    Kalderstam J, Sadik M, Edenbrandt L, Ohlsson M. Analysis of regional bone scan index measurements for the survival of patients with prostate cancer. BMC Med Imaging. 2014 Jul 10;14:24. doi: 10.1186/1471-2342-14-24. PubMed PMID: 25012268;
    PubMed Central PMCID: PMC4105506.

    Tokuda O, Harada Y, Ohishi Y, Matsunaga N, Edenbrandt L. Investigation of computer-aided diagnosis system for bone scans: a retrospective analysis in 406 patients. Ann Nucl Med. 2014 Feb 27. [Epub ahead of print] PubMed PMID: 24573796

    Edenbrandt L, Höglund P, Frantz S, Hasbak P, Johansen A, Johansson L, Kammeier A, Lindner O, Lomsky M, Matsuo S, Nakajima K, Nyström K, Olsson E, Sjöstrand K, Svensson SE, Wakabayashi H, Trägårdh E. Area of ischemia assessed by physicians and software packages from myocardial perfusion scintigrams. BMC Med Imaging. 2014 Jan 31;14(1):5. [Epub ahead of print] PubMed PMID: 24479846. Central PMCID: PMC3922637

    Johansson L, Edenbrandt L, Nakajima K, Lomsky M, Svensson SE, Trägårdh E. Computer-aided diagnosis system outperforms scoring analysis in myocardial perfusion imaging. J Nucl Cardiol. 2014 Jan 18. [Epub ahead of print] PMID:24442889

    Shafi A, Thorsson O, Edenbrandt L. New Routine for Nuclear Medicine Technologists to Determine When to Add SPECT/CT to a Whole-Body Bone Scan. J Nucl Med Technol. 2014 Mar;42(1):28-32. doi: 10.2967/jnmt.113.132035. Epub 2014 Jan 27. PubMed PMID: 24470596


    Andersson M, Johansson L, Minarik D, Mattsson S, Leide-Svegborn S. An internal radiation dosimetry computer program, IDAC 2.0, for estimation of patient doses from radiopharmaceuticals. Radiat Prot Dosimetry. 2013 Dec 18. [Epub ahead of print] PMID:24353030

    Nakajima K, Okuda K, Nyström K, Richter J, Minarik D, Wakabayashi H, Matsuo S, Kinuya S, Edenbrandt L. Improved quantification of small hearts for gated myocardial perfusion imaging. Eur J Nucl Med Mol Imaging. 2013 Aug;40(8):1163-70. doi: 10.1007/s00259-013-2431-x. Epub 2013 Apr 30. PMID: 23632963 Free PMC Article

    Johansen A, Lomsky M, Gerke O, Edenbrandt L, Johansson L, Hansen G, Jensen B, Reid MS, Johansson LL, Olofsson C, Minarik D, Nyström K, Wollmer P, Trägårdh E. When is reacquisition necessary due to high extra-cardiac uptake in myocardial perfusion scintigraphy? EJNMMI Res. 2013 Mar 25;3(1):20. doi: 10.1186/2191-219X-3-20. PMID: 23521849 Free PMC Article

    Edenbrandt L, Ohlsson M, Trägårdh E. Prognosis of patients without perfusion defects with and without rest study in myocardial perfusion scintigraphy. EJNMMI Res. 2013 Jul 31;3(1):58. [Epub ahead of print] PMID:23902737 Free PMC Article

    Trägårdh E, Valind S, Edenbrandt L. Adding attenuation corrected images in myocardial perfusion imaging reduces the need for a rest study. BMC Med Imaging. 2013 Apr 1;13:14. doi: 10.1186/1471-2342-13-14. PMID:23547878 Free PMC Article

    Kaboteh R, Gjertsson P, Leek H, Lomsky M, Ohlsson M, Sjöstrand K, Edenbrandt L. Progression of bone metastases in patients with prostate cancer - automated detection of new lesions and calculation of bone scan index. EJNMMI Res. 2013 Aug 16;3(1):64. doi: 10.1186/2191-219X-3-64. PMID:23947784 Free PMC Article

    Nakajima K, Nakajima Y, Horikoshi H, Ueno M, Wakabayashi H, Shiga T, Yoshimura M, Ohtake E, Sugawara Y, Matsuyama H, Edenbrandt L. Enhanced diagnostic accuracy for quantitative bone scan using an artificial neural network system: a Japanese multi-center database project. EJNMMI Res. 2013 Dec 26;3(1):83. doi: 10.1186/2191-219X-3-83. PMID:24369784 Free PMC Article

    Jakobson Mo S, Larsson A, Linder J, Birgander R, Edenbrandt L, Stenlund H, Forsgren L, Riklund K. ¹²³I-FP-Cit and 123I-IBZM SPECT uptake in a prospective normal material analysed with two different semiquantitative image evaluation tools. Nucl Med Commun. 2013 Oct;34(10):978-89. doi: 10.1097/MNM.0b013e328364aa2e. PMID:23903558

    Kaboteh R, Damber JE, Gjertsson P, Höglund P, Lomsky M, Ohlsson M, Edenbrandt L. Bone Scan Index: a prognostic imaging biomarker for high-risk prostate cancer patients receiving primary hormonal therapy. EJNMMI Res. 2013 Feb 6;3(1):9. doi: 10.1186/2191-219X-3-9. PMID:23384286 Free PMC Article

    Siennicki-Lantz A, André-Petersson L, Wollmer P, Elmståhl S. Depressive symptoms, atherosclerotic burden and cerebral blood flow disturbances in a cohort of octogenarian men from a general population. BMC Psychiatry. 2013 Dec 26;13:347. doi: 10.1186/1471-244X-13-347. PMID:24369109 Free PMC Article

    Furuäng L, Wollmer P, Siennicki-Lantz A, Elmståhl S. Cardiac ventricular dimensions predict cognitive decline and cerebral blood flow abnormalities in aging men. BMC Geriatr. 2013 May 15;13:45. doi: 10.1186/1471-2318-13-45. PMID:23672300 Free PMC Article

    Sydoff M, Lizana H, Mattsson S, Stabin MG, Leide-Svegborn S. Determination of the biodistribution and dosimetry of ¹²³I-FP-CIT in male patients with suspected Parkinsonism or Lewy body dementia using planar and combined planar and SPECT/CT imaging. Appl Radiat Isot. 2013 Dec;82:300-7. doi: 10.1016/j.apradiso.2013.09.006. Epub 2013 Sep 27. PMID:24135637

    Georgiadou E, Stenström KE, Uvo CB, Nilsson P, Skog G, Mattsson S. Bomb-pulse 14C analysis combined with 13C and 15N measurements in blood serum from residents of Malmö, Sweden. Radiat Environ Biophys. 2013 May;52(2):175-87. doi: 10.1007/s00411-013-0458-9. Epub 2013 Jan 29. PMID:23358598 Free PMC Article

    Mattsson S, Vañó E. ICRP perspective on criteria of acceptability for medical radiological equipment. Radiat Prot Dosimetry. 2013 Feb;153(2):158-60. doi: 10.1093/rpd/ncs296. Epub 2012 Nov 21. Review. PMID:23175639


    Trägårdh E, Sjöstrand K, Edenbrandt L. Normal stress databases in myocardial perfusion scintigraphy--how many subjects do you need? Clin Physiol Funct Imaging. 2012 Nov;32(6):455-62.

    Horikoshi H, Kikuchi A, Onoguchi M, Sjöstrand K, Edenbrandt L. Computer-aided diagnosis system for bone scintigrams from Japanese patients: importance of training database. Ann Nucl Med. 2012 Oct;26(8):622-6.

    Forberg JL, Khoshnood A, Green M, Ohlsson M, Björk J, Jovinge S, Edenbrandt L, Ekelund U. An artificial neural network to safely reduce the number of ambulance ECGs transmitted for physician assessment in a system with prehospital detection of ST elevation myocardial infarction. Scand J Trauma Resusc Emerg Med. 2012 Feb 1;20:8.

    Trägårdh E, Sjöstrand K, Jakobsson D, Edenbrandt L. Small average differences in attenuation corrected images between men and women in myocardial perfusion scintigraphy: a novel normal stress database. BMC Med Imaging. 2011 Oct 3;11:18.

    Tragardh E, Johansson LL, Olofsson C, Valind S, Edenbrandt L. Nuclear medicine technologists are able to accurately determine when a myocardial perfusion rest study is necessary. BMC Med Inform Decis Mak. 2012 Sep 4;12(1):97.

    Tragardh E, Höglund P, Ohlsson M, Wieloch M, Edenbrandt L. Referring physicians underestimate the extent of abnormalities in final reports from myocardial perfusion imaging. EJNMMI Res. 2012 Jun 9;2(1):27.

    Ly J, Garpered S, Höglund P, Jönsson E, Valind S, Edenbrandt L, Wollmer P. Semi-automatic analysis of standard uptake values in serial PET/CT studies in patients with lung cancer and lymphoma. BMC Med Imaging. 2012 Apr 2;12:6.

    Ulmert D, Kaboteh R, Fox JJ, Savage C, Evans MJ, Lilja H, Abrahamsson PA, Björk T, Gerdtsson A, Bjartell A, Gjertsson P, Höglund P, Lomsky M, Ohlsson M, Richter J, Sadik M, Morris MJ, Scher HI, Sjöstrand K, Yu A, Suurküla M, Edenbrandt L, Larson SM. A novel automated platform for quantifying the extent of skeletal tumour involvement in prostate cancer patients using the Bone Scan Index. Eur Urol. 2012 Jul;62(1):78-84. Epub 2012 Jan 27.

    Söderberg M, Mattsson S, Oddstig J, Uusijärvi-Lizana H, Valind S, Thorsson O, Garpered S, Prautzsch T, Tischenko O, Leide-Svegborn S. Evaluation of image reconstruction methods for 123I-MIBG-SPECT: a rank-order study. Acta Radiol. 2012 Sep 1;53(7):778-84. Epub 2012 Jul 30.

    Giussani A, Janzen T, Uusijärvi-Lizana H, Tavola F, Zankl M, Sydoff M, Bjartell A, Leide-Svegborn S, Söderberg M, Mattsson S, Hoeschen C, Cantone MC. A compartmental model for biokinetics and dosimetry of 18F-choline in prostate cancer patients. J Nucl Med. 2012 Jun;53(6):985-93. Epub 2012 May 8

    Leide-Svegborn S. External radiation exposure of personnel in nuclear medicine from 18F, 99mTC and 131I with special reference to fingers, eyes and thyroid. Radiat Prot Dosimetry. 2012 Apr;149(2):196-206. Epub 2011 May 12.

    Kikuchi A, Onoguchi M, Horikoshi H, Sjöstrand K, Edenbrandt L. Automated segmentation of the skeleton in whole-body bone scans: influence of difference in atlas. Nucl Med Commun. 2012 Sep;33(9):947-53.

    Hägerström D, Jakobsson D, Stomrud E, Andersson AM, Ryding E, Londos E, Minthon L, Rosén I, Edenbrandt L. A new automated method for analysis of rCBF-SPECT images based on the active-shape algorithm: normal values. Clin Physiol Funct Imaging. 2012 Mar;32(2):114-9. doi: 10.1111/j.1475-097X.2011.01063.x. Epub 2011 Nov 8.

    Bredenberg S, Dahlgren A, Mattsson S. Evaluation of a sieve classification method for characterization of low-dose interactive mixtures. Pharm Dev Technol. 2012 Sep 24. [Epub ahead of print]

    Geber-Bergstrand T, Bernhardsson C, Mattsson S, Rääf CL. Retrospective dosimetry using OSL of tooth enamel and dental repair materials irradiated under wet and dry conditions. Radiat Environ Biophys. 2012 Sep 13. [Epub ahead of print]

    Christiansson M, Mattsson S, Bernhardsson C, Rääf CL. Optimizing a readout protocol for low dose retrospective OSL-dosimetry using household salt. Health Phys. 2012 Jun;102(6):631-6. doi: 10.1097/HP.0b013e31824108f5.

    Mihaescu A, Thornberg C, Santén S, Mattsson S, Jeppsson B, Thorlacius H. Radiation-induced platelet-endothelial cell interactions are mediated by P-selectin and P-selectin glycoprotein ligand-1 in the colonic microcirculation. Surgery. 2012 Apr;151(4):606-11. Epub 2011 Dec 6.

    Tavola F, Janzen T, Giussani A, Facchinetti D, Veronese I, Uusijärvi-Lizana H, Mattsson S, Hoeschen C, Cantone MC.Nonlinear compartmental model of 18F-choline. Nucl Med Biol. 2012 Feb;39(2):261-8. Epub 2011 Dec 1.

    Oren U, Rääf CL, Mattsson S. Gafchromic film as a fast visual indicator of radiation exposure of first responders. Radiat Prot Dosimetry. 2012 Jun;150(1):119-23. Epub 2011 Sep 17.


    Edman Å, Edenbrandt L, Fredén-Lindqvist J, Nilsson M, Wallin A.  Asymmetric Cerebral Blood Flow in Patients with Mild Cognitive Impairment: Possible Relationship to Further Cognitive Deterioration. Dement Geriatr Cogn Disord Extra 2011;1:228–36.

    Gjertsson P, Johansson L, Lomsky M, Ohlsson M, Underwood SR, Edenbrandt L. Clinical data do not improve artificial neural network interpretation of myocardial perfusion scintigraphy. Clin Physiol
    Funct Imaging. 2011, May;31(3):240-5.

    Johansson L, Lomsky M, Marving J, Ohlsson M, Svensson SE, Edenbrandt L. Diagnostic evaluation of three cardiac software packages using a consecutive group of patients. Eur J Nucl Med Mol Imaging Research 1:22, 2011. http://www.ejnmmires.com/content/1/1/22.

    Landgren M, Sjöstrand K, Ohlsson M, Ståhl D, Overgaard N C, Åström K, Sixt R, Edenbrandt L. An Automated System for the Detection and Diagnosis of Kidney Lesions in Children from Scintigraphy Images. A.    Heyden and F Kahl (Eds): SCIA 2011, LNCS 6688. pp. 489-500, 2011. C
    Springer-Verlag Berlin Heidelberg 2011.

    Leide-Svegborn S. External radiation exposure of personnel in nuclear medicine from 18F, 99mTc and 131I with special reference to fingers, eyes and thyroid. Radiat Prot Dosimetry. 2011 May 12. [Epub ahead of print]

    Levren G, Sadik M, Gjertsson P, Lomsky M, Michanek A, Edenbrandt L. Relation between pain and skeletal metastasis in patients with prostate or breast cancer. Clin Physiol Funct Imaging. 2011, May;31(3):193-5.

    Ståhl D, Åström K, Overgaard N C, Landgren M, Sjöstrand K, Edenbrandt L. Automatic Compartment Modelling and Segmentation for Dynamical Renal Scintigraphies. A. Heyden and F Kahl (Eds): SCIA 2011, LNCS 6688. pp. 557-568, 2011. C Springer-Verlag Berlin Heidelberg 2011.

    Trägårdh E, Sjöstrand K, Jakobsson D, Edenbrandt L. Small average differences in attenuation corrected images between men and women in myocardial perfusion scintigraphy: a novel normal stress database. BMC Med Imaging. 2011 Oct 3;11(1):18. [Epub ahead of print]